I own Pilla's and for me, going from crappy yellow safety glasses to Pilla's did make a noticeable difference, especially in different light conditions. I was lucky enough to try a few different lenses from a chap who really has a 'collection' and sort out which ones work for me, and they do. Are they (stupid) expensive? Yep. Do they work? Yep. Do they make me miss less? Can't say that, but at least I see the clay a bit better even if I don't dust it.
It's the same with any flashy product: A five figure gun does not necessarily shoot better than a three figure gun, but there is something to be said for quality. Also, they wouldn't sell if they didn't work. Whether they work well enough for you to justify the spend is wholly personal.